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Enhancer-Promoter Communication: It’s Not Just About Contact

Cis-regulatory elements such as enhancers can be located even a million base pairs away from their cognate promoter and yet modulate gene transcription. Indeed, the 3D organisation of chromatin enables the establishment of long-range enhancer-promoter communication. The observation of long-range enh...

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Detalles Bibliográficos
Autores principales: Wurmser, Annabelle, Basu, Srinjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061983/
https://www.ncbi.nlm.nih.gov/pubmed/35517868
http://dx.doi.org/10.3389/fmolb.2022.867303