Extensive Chromatin Structure-Function Associations Revealed by Accurate 3D Compartmentalization Characterization

A/B compartments are observed in Hi-C data and coincide with eu/hetero-chromatin. However, many genomic regions are ambiguous under A/B compartment scheme. We develop MOSAIC (MOdularity and Singular vAlue decomposition-based Identification of Compartments), an accurate compartmental state detection...

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Detalles Bibliográficos
Autores principales: Wen, Zi, Zhang, Weihan, Zhong, Quan, Xu, Jinsheng, Hou, Chunhui, Qin, Zhaohui Steve, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062080/
https://www.ncbi.nlm.nih.gov/pubmed/35517497
http://dx.doi.org/10.3389/fcell.2022.845118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062080/
https://www.ncbi.nlm.nih.gov/pubmed/35517497
http://dx.doi.org/10.3389/fcell.2022.845118

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