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Extensive Chromatin Structure-Function Associations Revealed by Accurate 3D Compartmentalization Characterization
A/B compartments are observed in Hi-C data and coincide with eu/hetero-chromatin. However, many genomic regions are ambiguous under A/B compartment scheme. We develop MOSAIC (MOdularity and Singular vAlue decomposition-based Identification of Compartments), an accurate compartmental state detection...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062080/ https://www.ncbi.nlm.nih.gov/pubmed/35517497 http://dx.doi.org/10.3389/fcell.2022.845118 |