Insights into the stereoselectivity of human SETD7 methyltransferase

Human SETD7 methyltransferase (hSETD7) is involved in a wide range of physiological processes, and has been considered as a significant target to develop new drugs. (R)-PFI-2, one hSETD7 inhibitor, could bind to the pocket of substrates with potent (low nanomolar) activity and high selectivity, whil...

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Detalles Bibliográficos
Autores principales: Tang, Bowen, Li, Baicun, Li, Boqun, Qin, Jingbo, Zhao, Junming, Xu, Jianwenn, Qiu, Yingkun, Wu, Zhen, Fang, Meijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062083/
https://www.ncbi.nlm.nih.gov/pubmed/35517649
http://dx.doi.org/10.1039/c9ra00190e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062083/
https://www.ncbi.nlm.nih.gov/pubmed/35517649
http://dx.doi.org/10.1039/c9ra00190e

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