Alterations in 3D chromatin organization contribute to tumorigenesis of EGFR-amplified glioblastoma

BACKGROUND: EGFR amplification and/or mutation are found in more than half of the cases with glioblastoma. Yet, the role of chromatin interactions and its regulation of gene expression in EGFR-amplified glioblastoma remains unclear. METHODS: In this study, we explored alterations in 3D chromatin org...

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Detalles Bibliográficos
Autores principales: Yang, Qi, Jiang, Nian, Zou, Han, Fan, Xuning, Liu, Tao, Huang, Xi, Wanggou, Siyi, Li, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062087/
https://www.ncbi.nlm.nih.gov/pubmed/35521558
http://dx.doi.org/10.1016/j.csbj.2022.04.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062087/
https://www.ncbi.nlm.nih.gov/pubmed/35521558
http://dx.doi.org/10.1016/j.csbj.2022.04.007

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