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Oleamide-Mediated Polarization of M1 Macrophages and IL-1β Production by Regulating NLRP3-Inflammasome Activation in Primary Human Monocyte-Derived Macrophages

Macrophages are a type of innate immune cell that activates the NLRP3 inflammasome, causing the release of the cytokine IL-1β, which is a crucial mediator of the inflammatory response. NLRP3 activation that is dysregulated worsens a variety of inflammatory and autoimmune diseases, as well as neurode...

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Detalles Bibliográficos
Autores principales: Wisitpongpun, Prapakorn, Potup, Pachuen, Usuwanthim, Kanchana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062104/
https://www.ncbi.nlm.nih.gov/pubmed/35514993
http://dx.doi.org/10.3389/fimmu.2022.856296