Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy

Lipid droplets (LDs) are multifunctional organelles that regulate energy storage and cellular homeostasis. The first step of triacylglycerol hydrolysis in LDs is catalyzed by adipose triglyceride lipase (ATGL), deficiency of which results in lethal cardiac steatosis. Although hormone-sensitive lipas...

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Detalles Bibliográficos
Autores principales: Yamada, Mika, Suzuki, Jinya, Sato, Satsuki, Zenimaru, Yasuo, Saito, Rie, Konoshita, Tadashi, Kraemer, Fredric B., Ishizuka, Tamotsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062333/
https://www.ncbi.nlm.nih.gov/pubmed/35283217
http://dx.doi.org/10.1016/j.jlr.2022.100194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062333/
https://www.ncbi.nlm.nih.gov/pubmed/35283217
http://dx.doi.org/10.1016/j.jlr.2022.100194

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