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Improving the topology prediction of α-helical transmembrane proteins with deep transfer learning
Transmembrane proteins (TMPs) are essential for cell recognition and communication, and they serve as important drug targets in humans. Transmembrane proteins' 3D structures are critical for determining their functions and drug design but are hard to determine even by experimental methods. Alth...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062415/ https://www.ncbi.nlm.nih.gov/pubmed/35521551 http://dx.doi.org/10.1016/j.csbj.2022.04.024 |