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An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins

The PKC family consists of several closely related kinases. These enzymes regulate the function of proteins through the phosphorylation of hydroxyl groups on serines and/or threonines. The selective activation of individual PKC isozymes has proven challenging because of a lack of specific activator...

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Detalles Bibliográficos
Autores principales: Gada, Kirin D., Kawano, Takeharu, Plant, Leigh D., Logothetis, Diomedes E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062429/
https://www.ncbi.nlm.nih.gov/pubmed/35367414
http://dx.doi.org/10.1016/j.jbc.2022.101893