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An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins
The PKC family consists of several closely related kinases. These enzymes regulate the function of proteins through the phosphorylation of hydroxyl groups on serines and/or threonines. The selective activation of individual PKC isozymes has proven challenging because of a lack of specific activator...
Autores principales: | Gada, Kirin D., Kawano, Takeharu, Plant, Leigh D., Logothetis, Diomedes E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062429/ https://www.ncbi.nlm.nih.gov/pubmed/35367414 http://dx.doi.org/10.1016/j.jbc.2022.101893 |
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