Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses

Triglyceride (TG)-lowering LPL variants in combination with genetic LDL-C-lowering variants are associated with reduced risk of coronary artery disease (CAD). Genetic variation in the APOA5 gene encoding apolipoprotein A-V also strongly affects TG levels, but the potential clinical impact and underl...

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Detalles Bibliográficos
Autores principales: Ibi, Dorina, Boot, Manon, Dollé, Martijn E.T., Jukema, J. Wouter, Rosendaal, Frits R., Christodoulides, Constantinos, Neville, Matt J., Koivula, Robert, Rensen, Patrick C.N., Karpe, Fredrik, Noordam, Raymond, Willems van Dijk, Ko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062431/
https://www.ncbi.nlm.nih.gov/pubmed/35278410
http://dx.doi.org/10.1016/j.jlr.2022.100193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062431/
https://www.ncbi.nlm.nih.gov/pubmed/35278410
http://dx.doi.org/10.1016/j.jlr.2022.100193

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