Selective expansion of regulatory T cells by NKTR-358 in healthy volunteers and patients with systemic lupus erythematosus

OBJECTIVE: To evaluate NKTR-358, a polyethylene glycol-interleukin-2 conjugate composition designed to selectively induce regulatory T cells (Tregs), in first-in-human studies. METHODS: Healthy volunteers and patients with systemic lupus erythematosus (SLE) received single- or multiple-dose (biweekl...

Descripción completa

Detalles Bibliográficos
Autores principales: Fanton, Christie, Furie, Richard, Chindalore, Vishala, Levin, Robert, Diab, Isam, Dixit, Neha, Haglund, Cat, Gibbons, Jacqueline, Hanan, Nathan, Dickerson, Daniel, Zalevsky, Jonathan, Kotzin, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062472/
https://www.ncbi.nlm.nih.gov/pubmed/35517914
http://dx.doi.org/10.1016/j.jtauto.2022.100152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062472/
https://www.ncbi.nlm.nih.gov/pubmed/35517914
http://dx.doi.org/10.1016/j.jtauto.2022.100152

Ejemplares similares