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Selective expansion of regulatory T cells by NKTR-358 in healthy volunteers and patients with systemic lupus erythematosus

OBJECTIVE: To evaluate NKTR-358, a polyethylene glycol-interleukin-2 conjugate composition designed to selectively induce regulatory T cells (Tregs), in first-in-human studies. METHODS: Healthy volunteers and patients with systemic lupus erythematosus (SLE) received single- or multiple-dose (biweekl...

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Detalles Bibliográficos
Autores principales:	Fanton, Christie, Furie, Richard, Chindalore, Vishala, Levin, Robert, Diab, Isam, Dixit, Neha, Haglund, Cat, Gibbons, Jacqueline, Hanan, Nathan, Dickerson, Daniel, Zalevsky, Jonathan, Kotzin, Brian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062472/ https://www.ncbi.nlm.nih.gov/pubmed/35517914 http://dx.doi.org/10.1016/j.jtauto.2022.100152

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