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Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing

Extensive portions of the human genome have unknown function, including those derived from transposable elements. One such element, the DNA transposon Hsmar1, entered the primate lineage approximately 50 million years ago leaving behind terminal inverted repeat (TIR) sequences and a single intact co...

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Detalles Bibliográficos
Autores principales: Chen, Qiujia, Bates, Alison M., Hanquier, Jocelyne N., Simpson, Edward, Rusch, Douglas B., Podicheti, Ram, Liu, Yunlong, Wek, Ronald C., Cornett, Evan M., Georgiadis, Millie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062482/
https://www.ncbi.nlm.nih.gov/pubmed/35378129
http://dx.doi.org/10.1016/j.jbc.2022.101894