IL-34 Downregulation‒Associated M1/M2 Macrophage Imbalance Is Related to Inflammaging in Sun-Exposed Human Skin

Macrophages can be polarized into two subsets: a proinflammatory (M1) or an anti-inflammatory (M2) phenotype. In this study, we show that an increased M1-to-M2 ratio associated with a decrease in IL-34 induces skin inflammaging. The total number of macrophages in the dermis did not change, but the n...

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Detalles Bibliográficos
Autores principales: Horiba, Satoshi, Kami, Ryota, Tsutsui, Taiki, Hosoi, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062483/
https://www.ncbi.nlm.nih.gov/pubmed/35521044
http://dx.doi.org/10.1016/j.xjidi.2022.100112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062483/
https://www.ncbi.nlm.nih.gov/pubmed/35521044
http://dx.doi.org/10.1016/j.xjidi.2022.100112

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