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Multiple Reaction Monitoring-Mass Spectrometry Enables Robust Quantitation of Plasma Proteins Regardless of Whole Blood Processing Delays That May Occur in the Clinic

Plasma is an important biofluid for clinical research and diagnostics. In the clinic, unpredictable delays—from minutes to hours—between blood collection and plasma generation are often unavoidable. These delays can potentially lead to protein degradation and modification and might considerably affe...

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Detalles Bibliográficos
Autores principales: Gaither, Claudia, Popp, Robert, Zahedi, René P., Borchers, Christoph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062485/
https://www.ncbi.nlm.nih.gov/pubmed/35182769
http://dx.doi.org/10.1016/j.mcpro.2022.100212