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Targeting HER2-positive gastric cancer with a novel (18)F-labeled Z(HER2:342) probe

To realize the diagnosis of HER2-positive gastric cancer via PET imaging, herein, a new kind of (18)F-labeled HER2 affibody probe was created; the bifunctional maleimide derivative 1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA-MAL) was first coupled to a polypeptide, and the resulting compound...

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Detalles Bibliográficos
Autores principales: Pan, Yunyun, Yang, Zhengyang, Xu, Yuping, Bai, Zhicheng, Pan, Donghui, Yang, Runlin, Wang, Lizhen, Guan, Wenxian, Yang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062611/
https://www.ncbi.nlm.nih.gov/pubmed/35515328
http://dx.doi.org/10.1039/c8ra10271f