Enhancement of protein stability by an additional disulfide bond designed in human neuroglobin

Human neuroglobin (Ngb) forms an intramolecular disulfide bond between Cys46 and Cys55, with a third Cys120 near the protein surface, which is a promising protein model for heme protein design. In order to protect the free Cys120 and to enhance the protein stability, we herein developed a strategy b...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Hai-Xiao, Li, Lianzhi, Yang, Xin-Zhi, Wei, Chuan-Wan, Cheng, Hui-Min, Gao, Shu-Qin, Wen, Ge-Bo, Lin, Ying-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062612/
https://www.ncbi.nlm.nih.gov/pubmed/35520156
http://dx.doi.org/10.1039/c8ra10390a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062612/
https://www.ncbi.nlm.nih.gov/pubmed/35520156
http://dx.doi.org/10.1039/c8ra10390a

Ejemplares similares