Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase–pyrophosphatases that act via a covalent aspartyl–phosphate intermediate

Domain of Unknown Function 89 (DUF89) proteins are metal-dependent phosphohydrolases. Exemplary DUF89 enzymes differ in their metal and phosphosubstrate preferences. Here, we interrogated the activities and structures of two DUF89 paralogs from fission yeast—Duf89 and Duf8901. We find that Duf89 and...

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Detalles Bibliográficos
Autores principales: Sanchez, Ana M., Jacewicz, Agata, Shuman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062747/
https://www.ncbi.nlm.nih.gov/pubmed/35314193
http://dx.doi.org/10.1016/j.jbc.2022.101851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062747/
https://www.ncbi.nlm.nih.gov/pubmed/35314193
http://dx.doi.org/10.1016/j.jbc.2022.101851

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