ALKBH5 regulates STAT3 activity to affect the proliferation and tumorigenicity of osteosarcoma via an m6A-YTHDF2-dependent manner

BACKGROUND: N6-methyladenosine (m6A) is the most common and abundant mRNA modification and it plays crucial roles in many biological processes. However, as a key RNA demethylase, alkylation repair homolog protein 5 (ALKBH5) has not been well studied in human osteosarcoma. The present study sought to...

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Detalles Bibliográficos
Autores principales: Yang, Zechuan, Cai, Zhuo, Yang, Caihong, Luo, Zhengqiang, Bao, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062761/
https://www.ncbi.nlm.nih.gov/pubmed/35490460
http://dx.doi.org/10.1016/j.ebiom.2022.104019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062761/
https://www.ncbi.nlm.nih.gov/pubmed/35490460
http://dx.doi.org/10.1016/j.ebiom.2022.104019

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