Using Mendelian randomisation to identify opportunities for type 2 diabetes prevention by repurposing medications used for lipid management

BACKGROUND: Maintaining a healthy lifestyle to reduce type 2 diabetes (T2D) risk is challenging and additional strategies for T2D prevention are needed. We evaluated several lipid control medications as potential therapeutic options for T2D prevention using tissue-specific predicted gene expression...

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Detalles Bibliográficos
Autores principales: Khankari, Nikhil K., Keaton, Jacob M., Walker, Venexia M., Lee, Kyung Min, Shuey, Megan M., Clarke, Shoa L., Heberer, Kent R., Miller, Donald R., Reaven, Peter D., Lynch, Julie A., Vujkovic, Marijana, Edwards, Todd L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062817/
https://www.ncbi.nlm.nih.gov/pubmed/35500537
http://dx.doi.org/10.1016/j.ebiom.2022.104038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062817/
https://www.ncbi.nlm.nih.gov/pubmed/35500537
http://dx.doi.org/10.1016/j.ebiom.2022.104038

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