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Using Mendelian randomisation to identify opportunities for type 2 diabetes prevention by repurposing medications used for lipid management
BACKGROUND: Maintaining a healthy lifestyle to reduce type 2 diabetes (T2D) risk is challenging and additional strategies for T2D prevention are needed. We evaluated several lipid control medications as potential therapeutic options for T2D prevention using tissue-specific predicted gene expression...
Autores principales: | Khankari, Nikhil K., Keaton, Jacob M., Walker, Venexia M., Lee, Kyung Min, Shuey, Megan M., Clarke, Shoa L., Heberer, Kent R., Miller, Donald R., Reaven, Peter D., Lynch, Julie A., Vujkovic, Marijana, Edwards, Todd L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062817/ https://www.ncbi.nlm.nih.gov/pubmed/35500537 http://dx.doi.org/10.1016/j.ebiom.2022.104038 |
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