Non-Decarboxylative Ruthenium-Catalyzed Rearrangement of 4-Alkylidene-isoxazol-5-ones to Pyrazole- and Isoxazole-4-carboxylic Acids

[Image: see text] Treatment of 4-(2-hydroaminoalkylidenyl)- and 4-(2-hydroxyalkylidenyl)-substituted isoxazol-5(4H)-ones with catalytic amounts of [RuCl(2)(p-cymene)](2), without any additive, afforded pyrazole- and isoxazole-4-carboxylic acids, respectively. The presence of an intramolecular H-bond...

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Detalles Bibliográficos
Autores principales: Loro, Camilla, Molteni, Letizia, Papis, Marta, Lo Presti, Leonardo, Foschi, Francesca, Beccalli, Egle M., Broggini, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062882/
https://www.ncbi.nlm.nih.gov/pubmed/35439418
http://dx.doi.org/10.1021/acs.orglett.2c01135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062882/
https://www.ncbi.nlm.nih.gov/pubmed/35439418
http://dx.doi.org/10.1021/acs.orglett.2c01135

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