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A Potential Mechanism for Targeting Aggregates With Proteasomes and Disaggregases in Liquid Droplets
Insoluble protein deposits are hallmarks of neurodegenerative disorders and common forms of dementia. The aberrant aggregation of misfolded proteins involves a complex cascade of events that occur over time, from the cellular to the clinical phase of neurodegeneration. Declining neuronal health thro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062979/ https://www.ncbi.nlm.nih.gov/pubmed/35517053 http://dx.doi.org/10.3389/fnagi.2022.854380 |