Systematic evaluation and optimization of protein extraction parameters in diagnostic FFPE specimens

OBJECTIVES: Formalin-fixed paraffin-embedded (FFPE) tissue is the standard material for diagnostic pathology but poses relevant hurdles to accurate protein extraction due to cross-linking and chemical alterations. While numerous extraction protocols and chemicals have been described, systematic comp...

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Detalles Bibliográficos
Autores principales: Dressler, Franz F., Schoenfeld, Jana, Revyakina, Olga, Vogele, Daniel, Kiefer, Selina, Kirfel, Jutta, Gemoll, Timo, Perner, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063121/
https://www.ncbi.nlm.nih.gov/pubmed/35501693
http://dx.doi.org/10.1186/s12014-022-09346-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063121/
https://www.ncbi.nlm.nih.gov/pubmed/35501693
http://dx.doi.org/10.1186/s12014-022-09346-0

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