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Parvalbumin neuroplasticity compensates for somatostatin impairment, maintaining cognitive function in Alzheimer’s disease
BACKGROUND: Patient-to-patient variability in the degree to which β-amyloid, tau and neurodegeneration impact cognitive decline in Alzheimer’s disease (AD) complicates disease modeling and treatment. However, the underlying mechanisms leading to cognitive resilience are not resolved. We hypothesize...
Autores principales: | Morrone, Christopher Daniel, Lai, Aaron Yenhsin, Bishay, Jossana, Hill, Mary Elizabeth, McLaurin, JoAnne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063209/ https://www.ncbi.nlm.nih.gov/pubmed/35501886 http://dx.doi.org/10.1186/s40035-022-00300-6 |
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