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Chromosomal localization of cohesin is differentially regulated by WIZ, WAPL, and G9a

BACKGROUND: The cohesin complex is essential for proper chromosome structure and gene expression. Defects in cohesin subunits and regulators cause changes in cohesin complex dynamics and thereby alter three-dimensional genome organization. However, the molecular mechanisms that drive cohesin localiz...

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Detalles Bibliográficos
Autores principales: Justice, Megan, Bryan, Audra F., Limas, Juanita C., Cook, Jeanette Gowen, Dowen, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063240/
https://www.ncbi.nlm.nih.gov/pubmed/35501690
http://dx.doi.org/10.1186/s12864-022-08574-w