Expression-based species deconvolution and realignment removes misalignment error in multispecies single-cell data

BACKGROUND: Although single-cell RNA sequencing of xenograft samples has been widely used, no comprehensive bioinformatics pipeline is available for human and mouse mixed single-cell analyses. Considering the numerous homologous genes across the human and mouse genomes, misalignment errors should be...

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Detalles Bibliográficos
Autores principales: Choi, Jaeyong, Lee, Woochan, Yoon, Jung-Ki, Choi, Sun Mi, Lee, Chang-Hoon, Moon, Hyeong-Gon, Cho, Sukki, Chung, Jin-Haeng, Yang, Han-Kwang, Kim, Jong-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063264/
https://www.ncbi.nlm.nih.gov/pubmed/35501695
http://dx.doi.org/10.1186/s12859-022-04676-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063264/
https://www.ncbi.nlm.nih.gov/pubmed/35501695
http://dx.doi.org/10.1186/s12859-022-04676-0

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