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Nanoengineering a metal–organic framework for osteosarcoma chemo-immunotherapy by modulating indoleamine-2,3-dioxygenase and myeloid-derived suppressor cells

BACKGROUND: The high postoperative recurrence rate and refractoriness of relapsed tumors are still a conundrum for the clinical management of osteosarcoma (OS). New therapeutic options are urgently needed. Depriving the nourishment of myeloid-derived suppressor cells is a novel strategy to improve t...

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Detalles Bibliográficos
Autores principales: Fan, Qingxin, Zuo, Jing, Tian, Hailong, Huang, Canhua, Nice, Edouard C., Shi, Zheng, Kong, Qingquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063269/
https://www.ncbi.nlm.nih.gov/pubmed/35501823
http://dx.doi.org/10.1186/s13046-022-02372-8