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The accumulation of Vγ4 T cells with aging is associated with an increased adaptive Vγ4 T cell response after foodborne Listeria monocytogenes infection of mice

BACKGROUND: It is generally accepted that aging has detrimental effects on conventional T cell responses to systemic infections. However, most pathogens naturally invade the body through mucosal barriers. Although mucosal sites are highly enriched in unconventional immune sentinels like γδ T cells,...

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Detalles Bibliográficos
Autores principales: Khairallah, Camille, Chu, Timothy H., Qiu, Zhijuan, Imperato, Jessica N., Yang, Daniella, Sheridan, Brian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063344/
https://www.ncbi.nlm.nih.gov/pubmed/35501808
http://dx.doi.org/10.1186/s12979-022-00275-y