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Tunable chiral triazole-based halogen bond donors: assessment of donor strength in solution with nitrogen-containing acceptors

Strong halogen bond (XB) donors are needed for the activation of neutral substrates. We demonstrate that XB donor properties of iodo-triazoles can be significantly enhanced by quaternization in combination with varying the counterion and aromatic substituent, exemplified by association constants wit...

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Detalles Bibliográficos
Autores principales: Peterson, Anna, Kaasik, Mikk, Metsala, Andrus, Järving, Ivar, Adamson, Jasper, Kanger, Tõnis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063393/
https://www.ncbi.nlm.nih.gov/pubmed/35517004
http://dx.doi.org/10.1039/c9ra01692a