Receptor-Interacting Protein Kinase 3 Inhibition Relieves Mechanical Allodynia and Suppresses NLRP3 Inflammasome and NF-κB in a Rat Model of Spinal Cord Injury

BACKGROUND: Neuroinflammation is critical in developing and maintaining neuropathic pain after spinal cord injury (SCI). The receptor-interacting protein kinase 3 (RIPK3) has been shown to promote inflammatory response by exerting its non-necroptotic functions. In this study, we explored the involve...

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Detalles Bibliográficos
Autores principales: Xue, Song, Cao, Zhen-xin, Wang, Jun-nan, Zhao, Qing-xiang, Han, Jie, Yang, Wen-jie, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063406/
https://www.ncbi.nlm.nih.gov/pubmed/35514432
http://dx.doi.org/10.3389/fnmol.2022.861312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063406/
https://www.ncbi.nlm.nih.gov/pubmed/35514432
http://dx.doi.org/10.3389/fnmol.2022.861312

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