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PI3K Signaling in Dendritic Cells Aggravates DSS-Induced Colitis

Aberrant innate immune responses to the gut microbiota are causally involved in the pathogenesis of inflammatory bowel diseases (IBD). The exact triggers and main signaling pathways activating innate immune cells and how they modulate adaptive immunity in IBD is still not completely understood. Here...

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Detalles Bibliográficos
Autores principales: Kuttke, Mario, Hromadová, Dominika, Yildirim, Ceren, Brunner, Julia S., Vogel, Andrea, Paar, Hannah, Peters, Sophie, Weber, Maria, Hofmann, Melanie, Kerndl, Martina, Kieler, Markus, Datler, Hannes, Musiejovsky, Laszlo, Salzmann, Manuel, Lang, Michaela, Soukup, Klara, Halfmann, Angela, Sharif, Omar, Schabbauer, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063450/
https://www.ncbi.nlm.nih.gov/pubmed/35514976
http://dx.doi.org/10.3389/fimmu.2022.695576