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The caffeic acid moiety plays an essential role in attenuating lipid accumulation by chlorogenic acid and its analogues
Chlorogenic acid (5-caffeoylquinic, CA) possesses distinct hypolipidemic properties in vivo and in vitro, yet the structure–activity relationship (SAR) of CA on lipid metabolism remains unknown. To achieve this aim, we designed and synthesized two sets of CA analogues and evaluated their efficacies...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063487/ https://www.ncbi.nlm.nih.gov/pubmed/35515874 http://dx.doi.org/10.1039/c8ra09395d |