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The caffeic acid moiety plays an essential role in attenuating lipid accumulation by chlorogenic acid and its analogues

Chlorogenic acid (5-caffeoylquinic, CA) possesses distinct hypolipidemic properties in vivo and in vitro, yet the structure–activity relationship (SAR) of CA on lipid metabolism remains unknown. To achieve this aim, we designed and synthesized two sets of CA analogues and evaluated their efficacies...

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Detalles Bibliográficos
Autores principales: Cao, Xiaoxue, Wu, Chongming, Tian, Yu, Guo, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063487/
https://www.ncbi.nlm.nih.gov/pubmed/35515874
http://dx.doi.org/10.1039/c8ra09395d