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Forsythiaside inhibited titanium particle-induced inflammation via the NF-κB signaling pathway and RANKL-induced osteoclastogenesis and titanium particle-induced periprosthetic osteolysis via JNK, p38, and ERK signaling pathways

Wear particle-induced periprosthetic osteolysis is the primary complication of the total joint replacement; however, no conservative treatment except for reversal surgery is available for this disease. During the past decade, Chinese herbal medicines have been widely investigated to inhibit osteocla...

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Detalles Bibliográficos
Autores principales: Xu, Kaihang, He, Rongzhi, Zhang, Yuan, Qin, Sheng, Wang, Guangchao, Wei, Qiang, Zhang, Hao, Ji, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063541/
https://www.ncbi.nlm.nih.gov/pubmed/35515832
http://dx.doi.org/10.1039/c8ra10007a