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Altered Cholesterol Homeostasis in Huntington’s Disease

Huntington’s disease (HD) is an autosomal dominant genetic disorder caused by an expansion of the CAG repeat in the first exon of Huntingtin’s gene. The associated neurodegeneration mainly affects the striatum and the cortex at early stages and progressively spreads to other brain structures. Target...

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Detalles Bibliográficos
Autores principales: Kacher, Radhia, Mounier, Coline, Caboche, Jocelyne, Betuing, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063567/
https://www.ncbi.nlm.nih.gov/pubmed/35517051
http://dx.doi.org/10.3389/fnagi.2022.797220