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Dehydroquinate Synthase Directly Binds to Streptomycin and Regulates Susceptibility of Mycobacterium bovis to Streptomycin in a Non-canonical Mode

Antimicrobial resistance (AMR) represents one of the main challenges in Tuberculosis (TB) treatment. Investigating the genes involved in AMR and the underlying mechanisms holds promise for developing alternative treatment strategies. The results indicate that dehydroquinate synthase (DHQS) regulates...

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Detalles Bibliográficos
Autores principales: Wei, Wenping, Qiao, Junjie, Jiang, Xiaofang, Cai, Luxia, Hu, Xiaomin, He, Jin, Chen, Min, Yang, Min, Cui, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063660/
https://www.ncbi.nlm.nih.gov/pubmed/35516432
http://dx.doi.org/10.3389/fmicb.2022.818881