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Establishing a quantitative fluorescence assay for the rapid detection of kynurenine in urine

The kynurenine metabolite is associated with many diseases and disorders, ranging from diabetes and sepsis to more recently COVID-19. Here we report a fluorescence-based assay for the detection of kynurenine in urine using a specific chemosensor, 3-formyl-4-(ethylthio)-7-(diethylamino)-coumarin. The...

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Detalles Bibliográficos
Autores principales: Patel, Kamlesh, Fernandez-Villamarin, Marcos, Ward, Craig, Lord, Janet M., Tino, Peter, Mendes, Paula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063859/
https://www.ncbi.nlm.nih.gov/pubmed/35388832
http://dx.doi.org/10.1039/d2an00107a