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Rhynchophylline Regulates Calcium Homeostasis by Antagonizing Ryanodine Receptor 2 Phosphorylation to Improve Diabetic Cardiomyopathy

Diabetic cardiomyopathy (DCM) is a serious complication of diabetes that can lead to heart failure and death, for which there is no effective treatment. Rhynchophylline (Rhy) is the main effective component of the Chinese herbal medicine Uncaria rhynchophylla, which mainly acts on the cardiovascular...

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Detalles Bibliográficos
Autores principales: Liu, Jiao, Zhao, Yating, Zhu, Yufang, Wang, Yan, Liu, Xiaoshuang, Nie, Xiaobo, Zhao, Jing, Wang, Wei, Cheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063879/
https://www.ncbi.nlm.nih.gov/pubmed/35517784
http://dx.doi.org/10.3389/fphar.2022.882198