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Effects of Montelukast on Arsenic-Induced Epithelial-Mesenchymal Transition and the Role of Reactive Oxygen Species Production in Human Bronchial Epithelial Cells

Background: Epithelial-mesenchymal transition (EMT) of airway lung epithelial cells is considered a major driver of fibrosis and airway remodeling. Arsenic exposure is well known to cause the malignant transformation of cells, including those in the lung. Accumulating studies have shown that arsenic...

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Detalles Bibliográficos
Autores principales: Chen, Huang-Chi, Chiou, Hsin-Ying Clair, Tsai, Mei-Lan, Chen, Szu-Chia, Lin, Ming-Hong, Chuang, Tzu-Chun, Hung, Chih-Hsing, Kuo, Chao-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063880/
https://www.ncbi.nlm.nih.gov/pubmed/35517780
http://dx.doi.org/10.3389/fphar.2022.877125