Topotecan reduces sepsis‐induced acute lung injury and decreases the inflammatory response via the inhibition of the NF‐κB signaling pathway

This study aims to determine the function of topotecan (TPT) in acute lung injury (ALI) induced by sepsis. The mouse sepsis model was constructed through cecal ligation and puncture (CLP). The ALI score and lung wet/dry (W/D) weight ratio were applied to evaluate the level of lung injury. Hematoxyli...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoxia, Xu, Tianxiang, Jin, Jiajia, Ting Gao, M. M., Wan, Bing, Gong, Mei, Bai, Lingxiao, Lv, Tangfeng, Song, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063966/
https://www.ncbi.nlm.nih.gov/pubmed/35514783
http://dx.doi.org/10.1002/pul2.12070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063966/
https://www.ncbi.nlm.nih.gov/pubmed/35514783
http://dx.doi.org/10.1002/pul2.12070

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