Cargando…

Aza-BODIPY probe for selective visualization of cyclooxygenase-2 in cancer cells

AZB-IMC(2) was developed as a COX-2 specific probe that exhibited a brighter fluorescence signal in cancer cells that overexpress COX-2 compared to normal cells. Oxidative stress agent-treated inflamed cell lines inducing high COX-2 levels revealed an enhanced fluorescence signal. Inhibitory studies...

Descripción completa

Detalles Bibliográficos
Autores principales: Pewklang, Thitima, Chansaenpak, Kantapat, Lai, Rung-Yi, Noisa, Parinya, Kamkaew, Anyanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063976/
https://www.ncbi.nlm.nih.gov/pubmed/35519572
http://dx.doi.org/10.1039/c9ra01948k