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Synthesis of novel natural product-like diaryl acetylenes as hypoxia inducible factor-1 inhibitors and antiproliferative agents

The selaginellin derivatives are a type of novel natural pigments with an unusual alkynyl phenol skeleton from the genus Selaginella. Some of these natural compounds were previously reported to show important bioactivities, including anticancer activity, cardiovascular protection and phosphodiestera...

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Detalles Bibliográficos
Autores principales: Wang, Shisheng, Liu, Liqiang, Guo, Xiuhan, Li, Guangzhe, Wang, Xu, Dong, Huijuan, Li, Yueqing, Zhao, Weijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064011/
https://www.ncbi.nlm.nih.gov/pubmed/35519548
http://dx.doi.org/10.1039/c9ra02525a