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Using topic modeling to detect cellular crosstalk in scRNA-seq
Cell-cell interactions are vital for numerous biological processes including development, differentiation, and response to inflammation. Currently, most methods for studying interactions on scRNA-seq level are based on curated databases of ligands and receptors. While those methods are useful, they...
Autores principales: | Pancheva, Alexandrina, Wheadon, Helen, Rogers, Simon, Otto, Thomas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064087/ https://www.ncbi.nlm.nih.gov/pubmed/35395014 http://dx.doi.org/10.1371/journal.pcbi.1009975 |
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