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Pathological and immunological evaluation of different regimens of praziquantel treatment in a mouse model of Schistosoma mansoni infection

BACKGROUND: One of the considerable challenges of schistosomiasis chemotherapy is the inefficacy of praziquantel (PZQ) at the initial phase of the infection. Immature schistosomes are not susceptible to PZQ at the curative dose. Here, we investigated the efficacy of different PZQ regimens administer...

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Detalles Bibliográficos
Autores principales: Membe Femoe, Ulrich, Boukeng Jatsa, Hermine, Greigert, Valentin, Brunet, Julie, Cannet, Catherine, Kenfack, Mérimé Christian, Gipwe Feussom, Nestor, Kadji Fassi, Joseph Bertin, Tienga Nkondo, Emilenne, Abou-Bacar, Ahmed, Pfaff, Alexander Wilhelm, Dimo, Théophile, Kamtchouing, Pierre, Tchuem Tchuenté, Louis-Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064093/
https://www.ncbi.nlm.nih.gov/pubmed/35446855
http://dx.doi.org/10.1371/journal.pntd.0010382