Comparative molecular genomic analyses of a spontaneous rhesus macaque model of mismatch repair-deficient colorectal cancer

Colorectal cancer (CRC) remains the third most common cancer in the US with 15% of cases displaying Microsatellite Instability (MSI) secondary to Lynch Syndrome (LS) or somatic hypermethylation of the MLH1 promoter. A cohort of rhesus macaques from our institution developed spontaneous mismatch repa...

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Detalles Bibliográficos
Autores principales: Ozirmak Lermi, Nejla, Gray, Stanton B., Bowen, Charles M., Reyes-Uribe, Laura, Dray, Beth K., Deng, Nan, Harris, R. Alan, Raveendran, Muthuswamy, Benavides, Fernando, Hodo, Carolyn L., Taggart, Melissa W., Colbert Maresso, Karen, Sinha, Krishna M., Rogers, Jeffrey, Vilar, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064097/
https://www.ncbi.nlm.nih.gov/pubmed/35446842
http://dx.doi.org/10.1371/journal.pgen.1010163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064097/
https://www.ncbi.nlm.nih.gov/pubmed/35446842
http://dx.doi.org/10.1371/journal.pgen.1010163

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