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One-pot detection of telomerase activity with high sensitivity and specificity via RNA FRET probes and RNase H-assisted signal cycling amplification

Human telomerase is a universal cancer biomarker and a promising anticancer therapeutic target. Sensitive and specific detection of telomerase activity is of great significance for cancer diagnosis and treatment. Up to now, many methods have been established to detect the activity of telomerase, but...

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Detalles Bibliográficos
Autores principales: Wang, Honghong, Wang, Hui, Jia, Yuting, Zhang, Mai, Li, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064132/
https://www.ncbi.nlm.nih.gov/pubmed/35516338
http://dx.doi.org/10.1039/c9ra01816f