Metformin promotes proliferation and suppresses apoptosis in Ox-LDL stimulated macrophages by regulating the miR-34a/Bcl2 axis

Background: Metformin, an antidiabetic drug, has been reported to be involved in atherosclerosis (AS). In this study, the effects of metformin on oxidized low-density lipoprotein (Ox-LDL)-induced macrophage apoptosis were investigated, and the mechanisms involved in this process were examined. Metho...

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Detalles Bibliográficos
Autores principales: Feng, Liuliu, Liu, Tianhua, Yang, Yuya, Xiao, Wenying, Shi, Jun, Mei, Xiang, Tian, Songmei, Liu, Xinbing, Huang, Hongman, Bai, Yanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064147/
https://www.ncbi.nlm.nih.gov/pubmed/35516319
http://dx.doi.org/10.1039/c9ra00705a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064147/
https://www.ncbi.nlm.nih.gov/pubmed/35516319
http://dx.doi.org/10.1039/c9ra00705a

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