Computational analysis of hot spots and binding mechanism in the PD-1/PD-L1 interaction

Programmed cell death protein-1 (PD-1) is an important immunological checkpoint and plays a vital role in maintaining the peripheral tolerance of the human body by interacting with its ligand PD-L1. The overexpression of PD-L1 in tumor cells induces local immune suppression and helps the tumor cells...

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Detalles Bibliográficos
Autores principales: Huang, Dading, Wen, Wei, Liu, Xiao, Li, Yang, Zhang, John Z. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064197/
https://www.ncbi.nlm.nih.gov/pubmed/35516311
http://dx.doi.org/10.1039/c9ra01369e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064197/
https://www.ncbi.nlm.nih.gov/pubmed/35516311
http://dx.doi.org/10.1039/c9ra01369e

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