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Computational analysis of hot spots and binding mechanism in the PD-1/PD-L1 interaction

Programmed cell death protein-1 (PD-1) is an important immunological checkpoint and plays a vital role in maintaining the peripheral tolerance of the human body by interacting with its ligand PD-L1. The overexpression of PD-L1 in tumor cells induces local immune suppression and helps the tumor cells...

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Detalles Bibliográficos
Autores principales:	Huang, Dading, Wen, Wei, Liu, Xiao, Li, Yang, Zhang, John Z. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064197/ https://www.ncbi.nlm.nih.gov/pubmed/35516311 http://dx.doi.org/10.1039/c9ra01369e

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